Luton Weight Loss Services
Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, due to a mean loss of fluid, body fat or adipose tissue or lean mass, namely bone mineral deposits, muscle, tendon, and other connective tissue. Weight loss can either occur unintentionally due to malnourishment or an underlying disease or arise from a conscious effort to improve an actual or perceived overweight or obese state. “Unexplained” weight loss that is not caused by reduction in calorific intake or exercise is called cachexia and may be a symptom of a serious medical condition. Intentional weight loss is commonly referred to as slimming.
WEIGHT LOSS is not just about your diet plan, it is also about when you eat – and eating at the wrong times can cause you to pile on the pounds.
Weight loss is affected by the time that you eat your food, not just the diet plan that you choose to follow.
Do you know when you should be eating your main meals to shed the pounds effortlessly?
Endocrine disrupting chemicals in mixture and obesity, diabetes and related metabolic disorders
Obesity and associated metabolic disorders represent a major societal challenge in health and quality of life with large psychological consequences in addition to physical disabilities. They are also one of the leading causes of morbidity and mortality. Although, different etiologic factors including excessive food intake and reduced physical activity have been well identified, they cannot explain the kinetics of epidemic evolution of obesity and diabetes with prevalence rates reaching pandemic proportions. Interestingly, convincing data have shown that environmental pollutants, specifically those endowed with endocrine disrupting activities, could contribute to the etiology of these multifactorial metabolic disorders.
Regulation of energy metabolism relies on the integrated action of a large number of hormones operating centrally to control food behavior and peripherally to maintain glycaemia at a physiological range whilst covering energy demands. It both involves insulin secretion from pancreas and responsiveness to insulin by the metabolically active tissues (liver, muscle and adipose tissues) in response to food intake that elevates blood glucose. In addition to insulin, other hormones (and their corresponding high-affinity receptors) are involved in energy metabolism. They include, but are not limited to, glucocorticoids, thyroid hormone, leptin and adiponectin, gut hormones (such as ghrelin and Glucagon-like peptide 1 or GLP1), the growth hormone and the sexual hormones estrogen/androgen, energy metabolism being highly sexually marked with sex-dimorphic insulin sensitivity, eating behavior, distribution of fat, etc. The protective role of estrogens against metabolic disturbances has been well demonstrated conferring positive metabolic adaptations to women.
Obesity results in energy imbalance between energy intakes determined by food consumption and energy expenditure comprising basal metabolism and first signs of insulin resistance will arise in the metabolic tissues liver, muscle and adipose tissues. Importantly, lipid and glucose metabolisms are under a tight regulation not only by the hormones mentioned above and their associated hormone receptors but also by several nuclear receptors such as peroxisome proliferator-activated receptors (PPARs), liver X receptors (LXR) and farnesoid X receptor (FXR) as well as the xenosensors Pregnane X receptor (PXR), Constitutive androstane receptor (CAR) and aryl hydrocarbon receptor (AhR). These transcription factors integrate the changes in environmental or hormonal signals through direct gene regulation or through cross-talk with other transcriptional regulators to maintain the vital function of nutrient homeostasis between the fed and the fasting states. This concept does not exclude that pollutants may exert toxic effects by mechanisms distinct from endocrine disruption including oxidative stress and mitochondrial alteration as well as inflammation.
The pandemic evolution of obesity and its associated metabolic disorders that are considered as one of the major health burdens worldwide stress the need for extensive research towards the identification of new etiologic factors with the hope to prevent further augmentation and even more to reduce the kinetics of expansion. These past 20 years, evidences that endocrine disrupting compounds constitute etiologic factors have largely progressed. Certainly, more studies are to be undertaken to better determine the nature of the chemicals to which humans are exposed and at which level.
Are food intolerances making me gain weight?
Gluten Intolerance and Weight Gain
Historically, medical textbooks have presented Celiac disease patients as small, thin, anemic individuals, a depiction that still dominates many physicians’ views of gluten intolerance and the people who have it.
Recent research, however, is forcing a major re-thinking of that “classic” picture, and urging clinicians to be on the lookout for gluten sensitivity among people who are overweight or obese.
Described variously as an autoimmune disease or an allergy, Celiac disease affects the small intestine by reducing its total surface area. In sensitive individuals, presence of gluten in the gut instigates an inflammatory response, which over time destroys the fingerlike villi lining the inside of the small bowel.
Because the villi comprise most of the bowel’s surface area, damage caused by chronic inflammation can shrink the intestinal surface area. This severely compromises the bowel’s ability to absorb nutrients. Micronutrient absorption is particularly compromised, meaning that gluten-sensitive people are usually deficient in iron, calcium, and other minerals absorbed via the gut.
Previously, problems with absorption were thought to result in the short stature, low body weight, and tendency towards anemia that characterize the classical description of Celiac disease.
Overweight individuals believe they have some type of intestinal disorder like irritable bowel syndrome or a “sensitive” stomach. They can tell from their own experience that something is not right with their digestive systems, but they don’t really know what.
Even when the villi of the small bowel are damaged, as is the case in gluten-sensitive people, specialized cells in the large intestine can still absorb countless calories in the form of macronutrients like glucose. In order to take in adequate amounts of essential micronutrients, overweight individuals may have to consume a huge quantity of calories, which appears to be a potential cause of obesity.
Surrounded by mountains of cheap, processed foods, most people can now readily consume an unlimited amount of calories. Paradoxically, while many processed foods are fortified with vitamins and minerals, our bodies will absorb the macronutrients long before they absorb the micronutrients – leaving us overfed, yet undernourished.
Cooking as Clinical Intervention
A simple solution to the dual challenges of obesity and gluten sensitivity:
Learning to prepare fresh, healthy, gluten-free meals at home eliminates potential allergens and reduces the amount of processed foods that one consumes. It also offers greater control over portion sizing, flavors, and food-related expenses.
Even for those who are profoundly impressed by their results, the transition to a gluten-free lifestyle can be challenging.
While not everybody is gluten intolerant, and it’s certainly not the universal cause of obesity, we can all benefit from cooking our own food.
Lactose Intolerance and Weight Gain
Having lactose intolerance can’t cause you to gain weight, but it can cause a variety of other symptoms.
Lactose intolerance is the inability to digest lactose, which is milk sugar. You can also become lactose intolerant if your intestines have been affected by illness or if you’ve sustained an injury to the digestive tract.
We teach people how to cook, when to eat, what to eat and how to combine food to lose weight
We treat people for their metabolic deficiency.
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